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End of Life Online Curriculum - Modules

 

Pain Control: Opioid Conversion

Levy's Rule

Levy's Rule to convert from oral morphine to transdermal fentanyl

The fentanyl patch strength in micrograms is equal to half of the total dose of sustained release morphine given over 24 hours.
Source: Levy M. Pharmacologic treatment of cancer pain. N Engl J Med 1996;335:1124-32.
  1. Levy's Rule: Example 1 - Mr. John Smith, a terminally ill, lung cancer patient.
  2. Levy's Rule: Example 2 - Mr. Tom Hack, a terminally ill, colon cancer patient.

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©End of Life Curriculum Project, a joint project of the US Veterans Administration and SUMMIT, Stanford University Medical School.
Funded by a grant to the Veterans Administration Nationwide Palliative Care Network by the National Library of Medicine. VJ Periyakoil, MD, Director.